A cross-sectional research was conducted at Prof. Dr. Chairuddin P. Lubis Hospital of Universitas Sumatera Utara, Medan, Indonesia, from May 2023 to August 2023. Consecutive sampling method had been utilized to sample menopausal females without any history of hysterectomy or oophorectomy (unilateral or bilateral), and no reputation for hormone replacement treatment or supplement D supplementation. Interviews and real examinations were conducted to search for the faculties for the topics (age, length of time of menopausal, and the body size list). The 25(OH)D level ended up being measured making use of immunoassay and REMS evaluation was performed to evaluate BMD. The Spearman correlation test had been utilized to assess the correlation between serum vitamin D levels and BMD. An overall total of 32 menopausal women had been most notable study with the average vitamin D degree was 18.05±5.81 ng/mL, while the mean BMD amount ended up being -2.13±1.23. The data showed an important good correlation between serum vitamin D levels and BMD in menopausal women (r=0.710; p=0.020). This study highlights that REMS could be of good use as an alternative to dual-energy x-ray absorptiometry (DXA) to evaluate DMD in postmenopausal women.Coronavirus disease 2019 (COVID-19) is an infectious condition that develops rapidly causing a top case fatality rate in vulnerable populations. Neutrophil-lymphocyte proportion (NLR) and platelet-lymphocyte ratio (PLR) are recognized to be inflammatory biomarkers in a few infections medical news . The purpose of this study would be to determine the connection between NLR and PLR aided by the seriousness of COVID-19. A cross-sectional research was performed at Tabanan Regency General Hospital, Bali, Indonesia, from January 2021 to December 2022. All clients within the study tested good for COVID-19 by real-time polymerase string reaction (RT-PCR), aged 18-50 many years without any comorbid. Laboratory exams had been performed on entry. The customers had been classified into two teams based on the severity moderate and severe/critical. The Mann-Whitney test was made use of to determine the association between NLR and PLR with the extent of COVID-19. A total of 104 patients had been included in the study, the majority of COVID-19 patients had modest (77.9%) seriousness. The common NLR ended up being selleck chemicals 5.8 therefore the PLR had been 21.7. There clearly was a substantial relationship between NLR (p=0.002) and PLR (p=0.001) with the extent of COVID-19. The defined cut-off values of NLR and PLR were ≥3.8 and ≥106, producing sensitivities of 95% and 70%, and specificities of 74% and 50%, correspondingly. This research highlights the encouraging part of NLR and PLR as predictive biomarkers to assess COVID-19 severity.Studies have suggested associations between inflammatory markers utilizing the severity of coronavirus illness 2019 (COVID-19). Consequently, workouts that may reduce the level of inflammatory markers might be advantageous. The purpose of this research was to figure out the end result of top supply and breathing exercises on inflammatory markers such ferritin, lactate dehydrogenase (LDH), and C-reactive protein (CRP) in extreme COVID-19 patients. A quasi-experimental with pre-test and post-test control team design ended up being conducted among severe COVID-19 old 18-70 yrs old, with or without comorbidities. Baseline data of inflammatory markers (ferritin, LDH, and CRP) were assessed before the exercises and repeated post-exercise. The top of supply and respiration exercises were performed for ten times, twice a day (early morning and evening) for ten full minutes. A paired Student t-test ended up being utilized Paramedian approach to assess the alterations in the inflammatory markers’ levels. Our data suggested that quantities of ferritin and CRP were not significantly different between pre- and post-exercise. But, the level of LDH decreased dramatically from 481.35 U/L to 331.80 U/L (p=0.001). This study highlights that pulmonary rehabilitation exercises could be beneficial to enhance the recovery process in serious COVID-19 customers.Recent studies have demonstrated that cytokine dysregulation features a crucial part within the pathogenesis of dengue hemorrhagic temperature (DHF) and dengue shock syndrome (DSS). The goal of this study would be to explore the association between tumefaction necrosis factor (TNF- α), interleukin 6 (IL-6), interleukin 10 (IL-10), and interleukin 17 (IL-17) with disease standing, and extent of dengue. A prospective cross-sectional study was carried out at three hospitals in Gianyar regency and Denpasar municipality, Bali, Indonesia, from June to December 2022. Sixty-four dengue contaminated patients had been included. Clients’ serum was tested for dengue infection utilizing NS1 antigen rapid test, dengue virus immunoglobulin M (IgM) and immunoglobulin G (IgG) test, and reverse transcription polymerase chain reaction (RT-PCR). Cytokine levels (TNF-α, IL-6, IL-10, and IL-17) were assessed utilizing enzyme-linked immunosorbent assay (ELISA). Illness standing ended up being dependant on combining serological and RT-PCR results, categorizing customers into primary and secondary attacks. The current research unearthed that DF patients had reduced TNF-α, IL-6, and IL-17 but higher IL-10 amounts when compared with DHF clients (p less then 0.001). Elevated TNF-α, IL-6, and IL-17 levels were higher in secondary infection, while IL-10 degree had been higher in primary disease (p less then 0.001). In summary, cytokines play a vital role in the interplay between cytokine dysregulation and dengue illness characteristics.In Indonesia, malaria continues to be difficulty, with 94,610 active instances in 2021 and its particular current therapy includes chloroquine and artemisinin; nevertheless, opposition happens to be frequently reported. To conquer this dilemma, researches about possible medicinal flowers which you can use as antimalaria, such as for example moringa (Moringa oleifera) started initially to receive even more interest.