Most patients were taking PPI with other adjunctive therapy and for those who were taking multiple daily doses of PPI were using generic PPI. Almost 85% of patients experienced some breakthrough symptoms with 38% experienced nocturnal symptoms. Only 32% of respondents were taking a single dose of PPI. Most patients were taking the morning dose of PPI before breakfast. Patients were not fully satisfied with their current PPI therapy as only 13% of patients reported complete control of their symptoms. The remaining reported partial control (70%) and no control

at all (17%). Majority of patients desired 24-hour symptom control to provide nighttime relief. Most Patients felt that GERD

had negative impacts on quality of life despite being on PPI and significantly disrupted their daily living and work productivity. Conclusion: Conclusion: selleck chemicals llc From this survey, breakthrough AZD3965 chemical structure symptoms were common in PPI treated patients in Thailand and a significant proportion suffering from nocturnal symptoms. Patients were not completely satisfied with the control of their symptoms with current PPI therapy with or without adjunctive regimens. Key Word(s): 1. GERD; 2. PPI; 3. Patient survey; 4. Quality of life; Presenting Author: XING ZHANG Additional Authors: YIHONG FAN Corresponding Author: XING ZHANG Affiliations: zhejiang chinese medical university; Zhejiang Provincial Hospital Objective: To observe the influence on nausea and vomiting by wrist

electric acupuncture apparatus stimulating PC 6 and PC 5 combined with Granisetron for tumor patients undergoing chemotherapy. Methods: 72 tumor patients undergoing chemotherapy who met the inclusion criteria were randomly divided into control group and experimental group.34 cases were in the control group,and 38 cases the experimental group. We used wrist electric acupuncture apparatus to stimulate PC 6 and PC 5 (1 h,bid)combined with Granisetron(3 mg iv bid) for the experimental group while stimulating false PC 6 and false PC 5 for the control goup. To observe the vomiting times,nausea grade and overall efficacy in acute stage and delay stage. Results: ①there was no difference in vomiting times between the two groups in acute stage; patients in the control group nausead oxyclozanide more strongly,reaching a higher rank than the experimental group(p < 0.05)in delay stage; ②about overall efficacy, there was no difference between the two groups in acute stage, the experimental group obvious better than the control group in delay stage(p < 0.01); Conclusion: wrist electric acupuncture apparatus stimulating Neiguan point and Jianshi point combined with Granisetron could obviously reduce the nausea of tumor patients undergoing chemotherapy. Key Word(s): 1. electric acupuncture; 2. CINV; 3. PC 6; 4.