HEV RNA was undetectable at 4 months. Treatment was discontinued after 6 months and liver enzymes have remained normal to date. The patient denies receiving blood products. She does eat pork, oysters, and mussels. She drinks well water in her rural vacation home. She made several trips to Mexico and experienced an episode of fever

and gastrointestinal disturbance upon returning from a trip in 2002. HEV genotype 3 has been isolated in those click here who consumed pork products, mussels, and game meat.[1, 3, 4] Swine-associated HEV strains have been identified in sewage water[3] and can lead to shellfish contamination. It is tempting to speculate that this patient may have acquired HEV infection Ceritinib in vivo by consuming pork or shellfish. Recent studies in solid organ transplant recipients have shown that acute HEV genotype 3 infection or reactivation in anti-HEV IgG-positive transplant recipients can lead to chronic hepatitis with progression to cirrhosis.[4] Our patient also had HEV genotype 3 infection; the distant history of lupus may have predisposed her to the development of chronic HEV infection. This case highlights the importance of suspecting chronic HEV infection in patients with unexplained chronic hepatitis.

However, the lack of a standardized commercial nucleic acid-based assay in the U.S. to detect HEV RNA in stool or serum limits testing, although two commercially available RT-PCR RNA assays for HEV genotype

3 are reported in Europe.[7] Chronic HEV infections related to genotypes 1 and 2 have not been reported so far. An effective HEV vaccine has been approved in China following a controlled trial in 100,000 volunteers.[8] HEV vaccination would be very useful to prevent chronic HEV in immunosuppressed patients and those with chronic liver disease. “
” On behalf of the 2013 Scientific Program Committee, I welcome Fenbendazole you to Australian Gastroenterology Week and the Federation of Gastrointestinal Societies Meeting 2013 at the Melbourne Convention Centre, 7–9th October. This meeting is the focal point of the Gastroenterological Society of Australia’s (GESA) educational and scientific activities. In 2013, we meet again with our colleagues from the surgical societies ANZGOSA, ANZHPBA, CSSANZ, as well as our nursing colleagues from GENCA. We are delighted to report that there was an impressive number of abstract submissions this year (364), many of superb quality. These abstracts are published in the October supplement of the Journal of Gastroenterology and Hepatology, by discipline categories and within each discipline, in alphabetical order of primary authors. There is an author index on page XYZ to assist with referencing. Thank you again for your scientific contributions and support of GESA and the Federation of Gastrointestinal Societies’ major national meeting for 2013.