Patients with cirrhosis achieved SVR12 of 73% (24w). The adjusted SVR12 rate for 24w in patients with or without cirrhosis was significantly higher than the historical control. Summary of efficacy (FDV+DBV+RBV; ITT) C, patients with cirrhosis. Disclosures: Christoph Sarrazin – Advisory Committees or Review Panels: Boehringer Ingelheim, Vertex, Janssen, Merck/MSD, Gilead, Roche, Boehringer Ingelheim, Achillion, Janssen, Merck/MSD, Gilead, Roche; Consulting: Merck/MSD, Novartis, Merck/MSD, Novartis; Grant/Research Support: Abbott, Intermune, Roche, Merck/MSD, Gilead, Janssen, Abbott, Roche, Merck/MSD, Vertex, Gilead, Janssen; Speaking and Teaching: Bristol-Myers
Squibb, Gilead, Novartis, Abbott, Roche, Merck/MSD, Janssen, Siemens, Falk, Boehringer-Ingelheim,
Bristol-Myers Squibb, Gilead, Novartis, Abbott, Roche, Merck/MSD, Janssen, Siemens, www.selleckchem.com/products/CAL-101.html Falk, Boehringer-Ingelheim Francesco Castelli – Grant/Research Support: Astellas, Pfizer, Abbott; Independent Contractor: BMS, Boheringer Ingheleim, ViiV, Schering, Roche, Janssen Cilag, Novartis Massimo Puoti – Consulting: Abbvie Mitchell L. Shiffman – Advisory Committees or Review Panels: Merck, Gilead, Boehringer-Ingelheim, Bristol-Myers-Squibb, Abbvie, Janssen; Consulting: Roche/ Genentech, Gen-Probe; Grant/Research Support: Merck, Gilead, Boehring-er-Ingelheim, Bristol-Myers-Squibb, GSK, Abbvie, Beckman-Coulter, Achillion, Lumena, Intercept, Farnesyltransferase Novarit, Gen-Probe; Speaking and Teaching: Roche/Genen-tech, Merck, Gilead, GSK, Janssen, Bayer Xavier Forns – Consulting: Jansen, MSD, Abbvie; Grant/Research Support: Roche, MSD, Gilead Maria Buti NVP-LDE225 datasheet – Advisory Committees or Review Panels: Gilead, Janssen, Vertex, MSD; Grant/Research Support: Gilead, Janssen; Speaking and Teaching: Gilead, Janssen, Vertex,
Novartis Eric M. Yoshida – Advisory Committees or Review Panels: Hoffman LaRoche, Gilead Sciences Inc, Vertex Inc; Grant/Research Support: Abbvie, Hoffman LaRo-che, Merck Inc, Pfizer Inc, Norvartis Inc, Vertex Inc, Jannsen Inc, Gilead Sciences Inc, Boeringher Ingleheim Inc, Astellas; Speaking and Teaching: Gilead Sciences Inc, Cangene Corporation, Vertex Inc, Merck Inc Marc Bourlière – Advisory Committees or Review Panels: Schering-Plough, Bohringer inghelmein, Schering-Plough, Bohringer inghelmein; Board Membership: Bristol-Myers Squibb, Gilead, Idenix; Consulting: Roche, Novartis, Tibotec, Abott, glaxo smith kline, Merck, Bristol-Myers Squibb, Novartis, Tibotec, Abott, glaxo smith kline; Speaking and Teaching: Gilead, Roche, Merck, Bristol-Myers Squibb Jerry O. Stern – Employment: Boehringer Ingelheim Wulf O. Boecher – Employment: Boehringer Ingelheim GmbH George Kukolj – Employment: Boehringer Ingelheim Carla Haefner – Employment: Boehringer Ingelheim Pharma GmbH & co. KG Richard Vinisko – Employment: Boehringer-Ingelheim Miguel Garcia – Employment: Boehringer-Ingelheim Federico J.