The last 2 years’ case reports in English were scrutinized for noninfectious association with the rheumatic diseases. Cross-referencing from MEDLINE was performed using several databases including Google scholar; British Medical Journal (BMJ) case reports were also queried separately.
Recent findings
Fifty-three articles comprising
56 case reports are included in the review, with 27 (48.2%) associated with the vasculitides, eight (14.3%) associated with lupus and 13 (23.2%) were associated with the myositis syndromes. The commonest four groups of drugs to potentially induce rheumatic diseases were anti-tumour necrosis factor (TNF) drugs, oncology drugs, propylthiouracil and interferons.
Summary
It is important to recognise that drugs used in other specialties may induce rheumatic disease and vigilance on making a diagnosis Adavosertib in vitro is the key.”
“Objective. Early detection and treatment of chronic kidney
disease (CKD) is important for slowing the progression of the disease and decreasing the associated risk of cardiovascular disease. This study examined how two creatinine-based and two cystatin C-based equations for calculating estimated glomerular filtration rate (eGFR) perform relative to each other in identifying CKD in a large cohort of community-dwelling individuals. Material and methods. A total of 1630 adults were recruited from the RG-7388 ic50 Reykjavik area. Each subject’s eGFR was calculated using the Modification of Diet in Renal Disease (MDRD) Study and Cockroft-Gault equations, and two cystatin C-based equations.
The prevalence of decreased eGFR obtained by the four equations was compared Selleck Fedratinib and the relative performance of the equations examined. Results. The MDRD equation labelled significantly fewer individuals as having CKD (5.3%) relative to the other equations (12.8-19.7%). Agreement between equations was limited, with up to one-third of subjects diagnosed as having CKD by the MDRD equation being classified as normal by other equations. Correlations between creatinine- and cystatin C-based equations varied with age, gender and diuretic use. Conclusions. The MDRD equation results in lower population-wide estimates of CKD relative to the other equations tested. An understanding of the performance of these equations is critical when they are used for estimating the prevalence of CKD in a population-wide setting or for diagnosing the disorder in clinical practice.”
“AimTo compare the effectiveness of the double cervical cerclage method versus the single method in women with recurrent second-trimester delivery.
MethodIn this randomized clinical trial, we included 33 singleton pregnancies suffering from recurrent second-trimester pregnancy loss (2 consecutive fetal loss during second-trimester or with a history of unsuccessful procedures utilizing the McDonald method), due to cervical incompetence.